The patients who did not have such a good outcome had sequestra, thick walled abscesses, or uncontrolled dead spaces, all of which were amenable to surgical intervention because of the effect of streptomycin. In it Bosworth et al note that the use of streptomycin resulted in “dramatic healing of sinuses and a marked improvement in general physical condition” in about 80% of the 95 patients in their review. It documents the effectiveness of streptomycin in treating the draining sinuses of tuberculosis. ![]() The accompanying paper by Bosworth et al was published previously in CORR as a Classic Article. Rutgers University got 80% and with it built the Waksman Institute of Microbiology, which became a major research institution in that field. In the end Waksman got 10% of the money derived from the sale of the streptomycin patent, Schatz got 3%, and all others employed in the laboratory (and they were many) split 7%. Elizabeth Bugie, another worker in the laboratory, had only been asked to corroborate Schatz’s work, and she eventually withdrew from the civil action. Schatz, as a PhD worker in the laboratory, had done the work but only under Waksman’s direction and using Waksman’s methods. Waksman argued that he, as the director of the laboratory at Rutgers University, had spent 30 years perfecting the techniques that made the discovery possible. Elizabeth Bugie and Albert Schatz, Waksman’s putative collaborators, objected to Waksman’s one-sided winnings and eventually filed a lawsuit against him for what they considered to be their fair share. With the credit came fame and fortune, which included a Nobel Prize and medals and accolades from numerous nations, prestigious societies, and universities. ![]() Selman Waksman claimed (and received the credit for) the discovery of streptomycin in the mid 1940s). Selman Waksman (left) is shown with Sir Albert Fleming, who discovered penicillin.
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